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Dutasteride One
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Dutasteride
One™

The most effective hair loss medication available by prescription.

Most Men Wait Too Long. You're Here Early. That Matters.

Dutasteride blocks both Type I and Type II 5-alpha reductase — the two enzymes responsible for converting testosterone into DHT. Finasteride only blocks one. That’s why dutasteride suppresses scalp DHT more completely, produces greater hair count increases, and delivers superior results at every studied dose. This is the compound the data points to. Everything else is a compromise.

Prescribed by a licensed US physician. Dispensed from a LegitScript certified compounding pharmacy. Fresh medication compounded and shipped every 90 days.

Choose Your Strength
The Science Behind Each Dose · Olsen et al., J Am Acad Dermatol, 2006
0.5mg — Start Here
92%
Serum DHT Suppression
51%
Scalp DHT Suppression
The clinically established starting dose. More effective than finasteride 5mg at both serum and scalp level. Where every protocol begins.
1.5mg — Titration Dose
~94%
Serum DHT Suppression
~60–70%
Scalp DHT Suppression
For men with aggressive androgenetic alopecia. Physician-guided — your physician evaluates whether titrating up is appropriate after your first 90-day cycle.
2.5mg — After Titration
96%
Serum DHT Suppression
79%
Scalp DHT Suppression
Maximum studied dose. Available only after titrating through 1.5mg under physician guidance. Contact us to discuss.
vs. Finasteride 5mg (for comparison) 73% serum · 32% scalp
$125 $99 Save $26

0.5mg · First 90 days · $125/quarter after · Ships every 90 days

Welcome Discount

As a first-time MANE & STEEL member, your first 90 days are on us at a reduced rate. Our way of saying welcome to the team. Standard pricing applies at renewal.

Your Plan
Every 3 Months: Subscribe & Save

Ships every 90 days. Cancel before any renewal. Your subscription includes physician oversight, dosing guidance, and chat support from our team. We’re here for the long game with you.

Add to Cart

Telehealth-prescribed · US-licensed physicians · Discreet shipping · Cancel anytime

What Happens Next

Five Steps.
Then It Runs Itself.

1
Place Your Order
Select your protocol and complete checkout. Takes about 2 minutes.
2
Complete Your Health Intake
After purchase, a prompt will appear. Complete your health intake form. This takes a few minutes and is required for your prescription.
3
Physician Review
A licensed US physician reviews your intake, approves your protocol, and sends you a welcome message.
4
Shipped Discreetly
Your medication is dispensed from a LegitScript certified compounding pharmacy and delivered to your door in 7 to 10 days.
5
Automatic Renewal
Your subscription renews every 90 days. Fresh medication shipped automatically. Cancel before any renewal, no questions asked.