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Dutasteride One
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Dutasteride
One™

One Medication · Zero Compromise

The most effective hair loss medication available by prescription.

Most Men Wait Too Long. You're Here Early. That Matters.

Dutasteride blocks both Type I and Type II 5-alpha reductase — the two enzymes responsible for converting testosterone into DHT. Finasteride only blocks one. That’s why dutasteride suppresses scalp DHT more completely, produces greater hair count increases, and delivers superior results at every studied dose. This is the compound the data points to. Everything else is a compromise.

Prescribed by a licensed US physician. Dispensed from a LegitScript certified pharmacy using commercial-grade softgel capsules, shipped fresh every 90 days.

Choose Your Strength
1 softgel per day
Why softgels, not one compounded capsule?+
Our standard protocol uses commercially manufactured 0.5mg softgels — at 0.5mg, that's 1 softgel per day; at 1.5mg, that's 3 softgels per day; at 2.5mg, that's 5 softgels per day. We don't compound higher-dose dutasteride into a single custom capsule, and we don't compound dutasteride and minoxidil together into a single capsule. Compounded drugs aren't FDA-reviewed for safety, effectiveness, or quality the way commercial medications are, so we'd rather you take multiple commercial-grade softgels than have us represent a compounded capsule as identical to the real thing.
$135
$45/mo
3-Month Subscription · Ships Every 90 Days
Add to Cart

Ships every 90 days. Cancel before any renewal.

The Evidence

The Science Behind
Each Dose.

Percent reduction in scalp and serum DHT by dose · Olsen et al., J Am Acad Dermatol, 2006

0.5mg
92%
Serum DHT
51%
Scalp DHT
1.5mg
~94%
Serum DHT
~65%
Scalp DHT
2.5mg
96%
Serum DHT
79%
Scalp DHT
vs. Finasteride 5mg (for comparison) 73% serum · 32% scalp
2.5mg

Higher Dose.
See Where You Fit.

2.5mg wasn't built for every guy — it was built for guys who fit these profiles, and beyond. These are just three of the many profiles that fit the MAXXED dose. Everyone has the option, with full informed consent. That's why we're providing this.

Early-onset androgenetic alopecia
Profile 01
Early-Onset, Two-Pattern Loss (18–25)
Young men between 18 and 25 experiencing early-onset androgenetic alopecia — specifically with both crown loss and frontal loss — represent the most aggressive presentation. That's exactly the case a physician-guided conversation about the maximum studied dose is meant for.
Leave nothing on the table
Profile 02
Guys Who Won't Leave It On The Table
You live one life. For men who want the highest studied ceiling of DHT suppression — not because they necessarily need it, but because they want to know they gave it everything — 2.5mg is that option, with full informed consent behind it.
Guys on TRT
Profile 03
Guys On TRT
If you're on testosterone replacement therapy — especially at higher therapeutic doses — your body is converting more exogenous testosterone into DHT than baseline. 2.5mg dutasteride is the most complete tool available to mitigate that downstream effect.
Go Deeper

Read The Complete
Evidence Guide.

Reading the MANE & STEEL evidence guide

The Science Behind Higher-Dose Dutasteride

Read the full evidence guide — Olsen, Harcha, and Choi in detail, serum vs scalp DHT, and what informed consent means at 2.5mg.

View Guide
Your Medication

Commercial-Grade
Softgel Capsules.

Every dose of Dutasteride One™ ships as a commercial-grade, liquid-filled softgel capsule — each containing 0.5mg of dutasteride, so higher doses simply mean more softgels, exactly as your physician directs.

0.5mg
1 softgel
1.5mg
3 softgels
2.5mg
5 softgels

Exact capsule count is always subject to your pharmacy label and prescriber's instructions.

Are These Capsules Compounded?
No. We dispense commercial-grade dutasteride softgel capsules, sourced from approved suppliers — not custom-compounded powder-filled capsules. You can confirm the exact manufacturer on your prescription label or by contacting the pharmacy.
Is This The Same Delivery System As Avodart?
Yes. Avodart, the original branded dutasteride product, is also a liquid-filled soft gelatin capsule containing dutasteride dissolved in a lipid-based vehicle. Generic products can vary in inactive ingredients, so check your specific pharmacy label for exact details.
Why Is Dutasteride A Liquid-Filled Softgel?
Dutasteride has extremely poor water solubility and is highly lipophilic, so it's supplied as a commercial-grade, liquid-filled softgel — a solubilized, lipid-based formulation built to absorb more effectively than a dry powder capsule.
Why Do Higher Doses Require Multiple Capsules?
Commercial dutasteride softgels are manufactured in a 0.5mg strength. Higher prescribed doses are achieved by taking multiple 0.5mg capsules, always following the dosage and count printed on your prescription label.
What Happens Next

How To Complete
Your Order.

1
Place Your Order
Select your protocol. Takes about 2 minutes.
2
Health Intake
A quick form after checkout — required for your prescription.
3
Physician Review
A licensed US physician approves your protocol.
4
Shipped Discreetly
Delivered to your door via USPS.
5
Automatic Renewal
Renews every 90 days. Cancel anytime before renewal.